Search on: MITOGEN-ACTIVATED PROTEIN KINASE 1 
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Descriptor English:   Mitogen-Activated Protein Kinase 1 
Descriptor Spanish:   Proteína Quinasa 1 Activada por Mitógenos 
Descriptor Portuguese:   Proteína Quinase 1 Ativada por Mitógeno 
Synonyms English:   p42 MAPK
p42(Mitogen-Activated Protein Kinase)
Extracellular Signal-Regulated Kinase 2
p41 MAPK
p42 MAP Kinase
MAP Kinase 2
Mitogen-Activated Protein Kinase 2  
Tree Number:   D08.811.913.696.620.682.700.567.342.500
D08.811.913.696.620.682.700.646.750.249.500
D12.644.360.450.169.500
D12.776.476.450.169.500
Definition English:   A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms. 
Indexing Annotation English:   don't confuse MAP Kinase 2 with MAP KINASE KINASES referred to as MAP2 Kinases
History Note English:   2005(1992) 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   33471 
Unique Identifier:   D019950 

Occurrence in VHL:
 

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